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SR1555 hydrochloride - CAS 2309312-90-9
SR1555 hydrochloride - CAS 2309312-90-9
SKU:MF-0122403-01
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Product Details
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Bioactivity
SR1555 hydrochloride is the hydrochloride salt form of SR1555. It acts as an inverse agonist for the retinoic acid receptor-related orphan receptor γ (RORγ), with an IC50 of 1 μM. This compound inhibits the development and function of pro-inflammatory TH17 cells while increasing the frequency of anti-inflammatory regulatory T (Treg) cells. SR1555 hydrochloride is utilized in research related to autoimmune diseases.
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CAS Number
2309312-90-9
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Molecular Formula
C22H23ClF6N2O2
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Molecular Weight
496.87
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SMILES
Cl.O=C(N1CCN(CC2=CC=C(C=C2)C=3C=CC(=CC3)C(O)(C(F)(F)F)C(F)(F)F)CC1)C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound