SSAA09E1 - CAS 433212-75-0

SSAA09E1 is an inhibitor of severe acute respiratory syndrome coronavirus (SARS-CoV) viral entry.1It reduces infection of HEK293T cells transiently transfected with angiotensin-converting enzyme 2 (ACE2) by an HIV-based virus system pseudotyped with SARS-CoV surface glycoprotein (EC50= 6.7 μM) . SSAA09E1 also inhibits the proteolytic activity of cathepsin L (IC50= 5.33 μM) but not cathepsin B when used at a concentration of 20 μM.

Others, SARS-CoV, Cysteine Protease

Microbiology/Virology, Proteases/Proteasome, Others

433137

C7H9N3S2

199.3

C(=N/NC(N)=S)(\C)/C1=CC=CS1

-20°C

Ice Packs

Small Compound