SSTR5 antagonist 3 - CAS 2851454-42-5

SSTR5 antagonist 3 (Compound 23) serves as a potent somatostatin receptor subtype 5 (SSTR5) antagonist, demonstrating oral activity and minimal hERG inhibition. It shows significant efficacy, with IC50 values of 2.8 nM in humans and 1.4 nM in mice. This compound is utilized in gallstone research [1].

Somatostatin

GPCR/G Protein

2851454-42-5

C31H36F2N2O5

554.62

O(CC)C1=C(C(OCC)=CC(CN2CCC(CNC3=CC(OC)=C(C(O)=O)C=C3)(F)CC2)=C1)C4=CC=C(F)C=C4

-20°C

Ice Packs

Small Compound