ST-539 - CAS 1040754-67-3

ST-539 is an inhibitor of the deubiquitinating enzyme USP30, with an IC50 of 0.37 μM. It enhances the ubiquitination of mitochondrial proteins and induces mitophagy (autophagy), thereby regulating mitochondrial homeostasis. ST-539 is applicable for research in neurodegenerative diseases.

DUB, Autophagy

Ubiquitination, Autophagy, Cell Cycle/Checkpoint, DNA Damage/DNA Repair

1040684

C30H31N3O4S

529.65

O=C(NC(C(=O)NC1=CC=CC=2C1=CC=CC2S(=O)(=O)NC(C)(C)C)CC=3C=CC=CC3)C=4C=CC=CC4

-20°C

Ice Packs

Small Compound