STAT3-IN-24, cell-permeable - CAS 400628-16-2

STAT3-IN-24, a cell-permeable (PpYLKTK-mts) peptide inhibitor, obstructs the recruitment of STAT3 to Jak2 and inhibits the phosphorylation of Y705, thereby preventing STAT3 dimerization and nuclear translocation [1].

STAT

JAK/STAT signaling, Stem Cells

400628-16-2

C92H157N20O24P

1958.32

C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=C(OP(=O)(O)O)C=C1)NC(=O)[C@@H]2CCCN2)=O)CC(C)C)=O)CCCCN)=O)[C@@H](C)O)=O)CCCCN)=O)C)=O)C)=O)C(C)C)=O)CC(C)C)=O)CC(C)C)(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N4[C@H](C(O)=O)CCC4)C)=O)C)=O)CC(C)C)=O)CC(C)C)=O)C(C)C)=O)CCC3

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