STAT3-IN-39 - CAS 3037596-35-0

STAT3-IN-39 (compound 10K) is an orally active inhibitor of STAT3, demonstrating effective inhibition of STAT3 phosphorylation with an IC50 of 0.47 μM in NIH-3T3 cells. It hinders TGF-β1-induced fibrotic responses and prevents epithelial-mesenchymal transition in A549 cells. STAT3-IN-39 is applicable for research related to idiopathic pulmonary fibrosis.

STAT

JAK/STAT signaling, Stem Cells

3037561

C20H17F3N2O3S

422.42

O=C(C1=CC=2C=CC=CC2S1(=O)=O)N3CCN(CC4=CC(F)=C(F)C=C4F)CC3

-20°C

Ice Packs

Small Compound