Stellettin B - CAS 184885-91-4

Stellettin B, a triterpene compound isolated from the marine sponge Jaspis stellifera, has demonstrated notable anticancer properties. It induces G1 phase arrest, apoptosis, and autophagy in human non-small cell lung cancer A549 cells by inhibiting the PI3K/Akt/mTOR pathway. Additionally, Stellettin B reduces migration and invasion in hepatocellular carcinoma cells through the suppression of the MAPK and FAK/PI3K/AKT/mTOR signaling pathways. This compound is utilized in various cancer research studies.

FAK, mTOR, PI3K, Autophagy, Apoptosis, Akt

Apoptosis, PI3K/Akt/mTOR signaling, Angiogenesis, Cytoskeletal Signaling, Autophagy, Tyrosine Kinase/Adaptors

184885-91-4

C30H38O4

462.62

C[C@@]1\2[C@]([C@]3(C)[C@@](CC1)(C(C)(C)C(=O)CC3)[H])(CC(=O)/C2=C(\C=C\C=C(/C)\C=4OC(=O)C(C)=CC4)/C)[H]

-20°C

Ice Packs

Natural Product