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Molfinity

STING agonist-12 - CAS 2259624-71-8

STING agonist-12 - CAS 2259624-71-8

SKU:MF-0014806-01

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  • Bioactivity

    STING activator Compound 53 based on an oxindole core structure demonstrated robust on-target functional activation of STING (human EC50 185 nM) in immortalised and primary cells and a cytokine induction fingerprint consistent with STING activation.

  • Target

    STING

  • Related Pathways

    Immunology/Inflammation

  • CAS Number

    2259545

  • Purity

    0.9829

  • Molecular Formula

    C25H19ClF4N2O2

  • Molecular Weight

    490.88

  • SMILES

    CC1(C)C(=O)N(Cc2c(F)cccc2Cl)c2cc(ccc12)C(=O)NCc1c(F)cc(F)cc1F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound