STING Agonist 12b - CAS 2411100-70-2

STING agonist 12b is an agonist of stimulator of interferon genes (STING) .1It binds to STING (Kd= 26.4 μM) and induces interferon reporter gene expression in cells expressing human or mouse STING (EC50s = 7.45 and 10.23 μM, respectively) . STING agonist 12b (40 μM) induces expression of TNF-a, IL-6, IP-10, and IL-1b in THP-1 cells.

Others, STING

Immunology/Inflammation, Others

2411028

C16H15NO2

253.3

O=C1C=2C(NC=3C1=CC=C(C)C3C)=CC=C(OC)C2

-20°C

Ice Packs

Small Compound