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STING agonist-25 - CAS 2408723-10-2
STING agonist-25 - CAS 2408723-10-2
SKU:MF-0146840-01
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Product Details
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Bioactivity
STING agonist-23 (CF505) is a non-nucleotide, small-molecule compound that stimulates STING, enhancing the phosphorylation of STING, TBK1, and IRF3. It elevates the production of IFN-β, IL-6, CXCL-10, TNF-α, ISG-15, and CCL-5 in tumor cells and demonstrates efficacy against SARS-CoV strains [1].
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Target
Others, STING
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Related Pathways
Immunology/Inflammation, Others
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CAS Number
2408711
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Molecular Formula
C36H41N13O6
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Molecular Weight
751.79
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SMILES
C(/C=C/CN1C=2C(N=C1NC(=O)C=3N(CC)N=C(C)C3)=CC(C(N)=O)=CN2)N4C=5C(N=C4NC(=O)C=6N(CC)N=C(C)C6)=CC(C(N)=O)=CC5OCCCO
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound