STING agonist-35 - CAS 2228891-94-7

STING agonist-35 (Compound 1a) is an agonist for stimulator of interferon genes (STING), activating wild type STING and mutated type STING (R232H) at rates of 99% and 92%, respectively. It is a potent payload for ADC [1].

ADC Cytotoxin, STING

Antibody-drug Conjugate/ADC Related, Immunology/Inflammation

2228891-94-7

C21H20F2N8Na2O11P2S

738.42

OC1[C@]2([H])[C@H](N3C4=C(C(N=CN4)=O)C(F)=C3)O[C@]1([H])COP([S-])(O[C@]5([H])[C@@](O[C@@H](N6C7=NC=NC(N)=C7N=C6)[C@@H]5F)([H])COP(O)(O2)=O)=O.[Na+]

-20°C

Ice Packs

Small Compound