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STING agonist-43 - CAS 2882097-31-4

STING agonist-43 - CAS 2882097-31-4

MF-0118433-01

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Product Details

  • Bioactivity

    STINGagonist-43 (Compound 67) is a selective STING agonist with an EC50 of 20.53 μM. It selectively enhances the cGAMP-dependent STING pathway activation by modulating STING oligomerization. STINGagonist-43 demonstrates antitumor activity in a B16.F10 mouse melanoma model and can be utilized in cancer immunotherapy research.

  • Target

    STING

  • Related Pathways

    Immunology/Inflammation

  • CAS Number

    2882062

  • Molecular Formula

    C21H23NO4

  • Molecular Weight

    353.41

  • SMILES

    O=C(OCC)CN1C2=CC=C(C=C2C(=O)C3=CC(OC)=C(C(=C31)C)C)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound