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STING-IN-15 - CAS 2912492-05-6
STING-IN-15 - CAS 2912492-05-6
SKU:MF-0115483-01
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Product Details
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Bioactivity
STING-IN-15 (compound 66) is a potent STING inhibitor, effectively suppressing human and mouse STING with IC50 values of 116 nM and 96.3 nM, respectively. In the REX1 D18N mouse model, STING-IN-15 significantly reduces tissue damage and inflammation.
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Target
STING
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Related Pathways
Immunology/Inflammation
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CAS Number
2912492-05-6
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Molecular Formula
C20H14F2N4O3
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Molecular Weight
396.35
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SMILES
N(C(NC=1C=C2C(=CC1)OC(F)(F)O2)=O)C=3C=4C(NC3)=CC=C(/C=C/CC#N)C4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound