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STING-IN-7 - CAS 899947-07-0
STING-IN-7 - CAS 899947-07-0
SKU:MF-0158449-01
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Product Details
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Bioactivity
STING-IN-7 (compound 21) is a potent inhibitor of the stimulator of interferon genes (STING) pathway, with an inhibitory concentration (IC50) of 11.5 nM, effectively hampering the phosphorylation of both STING and interferon regulatory factor 3 (IRF3) [1].
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Target
STING
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Related Pathways
Immunology/Inflammation
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CAS Number
899947-07-0
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Molecular Formula
C16H14ClN3O
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Molecular Weight
299.76
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SMILES
CC1=C(Cl)C=C(NC(=O)NC2=CNC3=C2C=CC=C3)C=C1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound