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Molfinity

STL127705 - CAS 1326852-06-5

STL127705 - CAS 1326852-06-5

MF-0019903-01

$60.08 USD
$60.08 USD
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Product Details

  • Bioactivity

    STL127705 (Compound L) is a potent inhibitor of the Ku 70/80 heterodimer protein, disrupting Ku70/80-DNA interaction with an IC50 of 3.5 μM, and inhibiting Ku-dependent DNA-PKCS kinase activation with an IC50 of 2.5 μM.

  • Target

    Apoptosis, DNA-PK

  • Related Pathways

    DNA Damage/DNA Repair, PI3K/Akt/mTOR signaling, Apoptosis

  • CAS Number

    1326852-06-5

  • Purity

    0.9981

  • Molecular Formula

    C22H20FN5O4

  • Molecular Weight

    437.42

  • SMILES

    COc1ccc(CCNc2ncc3c(n2)[nH]c(=O)n(-c2cccc(F)c2)c3=O)cc1OC

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound