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Streptozotocin - CAS 18883-66-4
Streptozotocin - CAS 18883-66-4
SKU:MF-0009238-01
Regular price
$32.42 USD
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Sale price
$32.42 USD
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Product Details
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Bioactivity
Streptozotocin (Streptozocin, NSC-85998) is an antibiotic that enters pancreatic β-cells via the glucose transporter (GLUT2) and induces DNA methylation, leading to β-cell apoptosis. It is toxic to insulin-producing cells and commonly used to establish diabetic animal models. This product is unstable in solution and is recommended to be prepared freshly before use.
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Target
Autophagy, DNA Alkylator/Crosslinker, DNA Alkylation, DNA/RNA Synthesis, Antibiotic, Antibacterial
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Related Pathways
Cell Cycle/Checkpoint, Autophagy, DNA Damage/DNA Repair, Microbiology/Virology
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CAS Number
18813
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Purity
>99.99%
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Molecular Formula
C8H15N3O7
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Molecular Weight
265.22
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SMILES
[C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)(NC(N(N=O)C)=O)C=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Natural Product