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Molfinity

SU16f - CAS 251356-45-3

SU16f - CAS 251356-45-3

MF-0034092-01

$39.15 USD
$39.15 USD
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Product Details

  • Bioactivity

    SU16f (3-substituted indolin-2-one 16f) is a potent and selective PDGFRβ inhibitor (IC50s: 10 nM, 140 nM, 2.29 μM for PDGFRβ, PDGFR1, PDGFR2, respectively) . Neutralization of PDGFRβ receptor by SU16f blocks the promoting role of GC-MSCs conditioned medium in gastric cancer cell proliferation and migration.

  • Target

    PDGFR

  • Related Pathways

    Angiogenesis, Tyrosine Kinase/Adaptors

  • CAS Number

    251308

  • Purity

    0.9838

  • Molecular Formula

    C24H22N2O3

  • Molecular Weight

    386.44

  • SMILES

    C(=C1C=2C(=CC(=CC2)C3=CC=CC=C3)NC1=O)C4=C(C)C(CCC(O)=O)=C(C)N4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound