Succinyl phosphonate - CAS 26647-82-5

Succinyl phosphonate is a selective α-ketoglutarate dehydrogenase (α-KGDHC) and OGDHC inhibitor that inhibits α-ketoglutarate oxidative decarboxylation. Succinyl phosphonate trisodium salt inhibits glutamate-induced ROS generation in glutamate-stimulated hippocampal neurons and can be used to study neurodegenerative diseases.

Reactive Oxygen Species, ROS, Endogenous Metabolite

Immunology/Inflammation, NF-κB, Metabolism

26560

C4H7O6P

182.07

O=C(O)CCC(=O)P(=O)(O)O

-20°C

Ice Packs

Small Compound