Sulconazole mononitrate - CAS 61318-91-0

Sulconazole mononitrate (Exelderm) is the nitrate salt form of sulconazole, a synthetic imidazole derivative with the antifungal property. Sulconazole mononitrate inhibits fungal cytochrome P-450 sterol C-14 alpha-demethylation, resulting in the accumulation of fungal 14 alpha-methyl sterols and inhibition of the synthesis of ergosterol, an important component of the fungal cell membrane. Inhibition of ergosterol synthesis leads to a disruption of cell membrane permeability, and ultimately inhibition of cell wall synthesis. In addition, Sulconazole mononitrate seems to interfere with the autolytic degradation of fungal DNA and RNA.

Antifungal, Antibacterial, Antibiotic

Microbiology/Virology

61227

0.9992

C18H15Cl3N2S·HNO3

460.76

c1cc(ccc1CSC(Cn1ccnc1)c1c(cc(cc1)Cl)Cl)Cl.[N+](=O)(O)[O-]

-20°C

Ice Packs

Small Compound