Sulfo-DGN462 sodium - CAS 1401203-09-5

Sulfo-DGN462 sodium undergoes degradation to DGN462 when subjected to culture medium and plasma. DGN462, a highly effective DNA-alkylating agent, exhibits anti-tumor properties that are particularly active against acute myeloid leukemia (AML) .

DNA Alkylator/Crosslinker, ADC Cytotoxin

DNA Damage/DNA Repair, Antibody-drug Conjugate/ADC Related

1401203-09-5

C53H60N5NaO12S2

1046.19

[Na].[H][C@@]12Cc3ccccc3N1C(=O)c1cc(OC)c(OCc3cc(COc4cc5NC([C@]6([H])Cc7ccccc7N6C(=O)c5cc4OC)S(O)(=O)=O)cc(c3)N(CCOCCOCCOC)CC(C)(C)S)cc1NC2

-20°C

Ice Packs

Small Compound