Sulindac sulfide - CAS 49627-27-2

Sulindac sulfide (cis-Sulindac sulfide) is a non-steroidal anti-inflammatory compound that has a high affinity for COX-1 and acts as an inhibitor in Ras activation of Raf-1. Sulindac sulfide is a non-competitive inhibitor of gamma-secretase with an IC50 value of 20.2 μM. It is an active metabolite of sulinic acid.

AChR, Gamma-secretase, Raf, Drug Metabolite

Neuroscience, MAPK, Stem Cells, Metabolism, Proteases/Proteasome

49598

>99.99%

C20H17FO2S

340.41

C(=C/1\C=2C(C(CC(O)=O)=C1C)=CC(F)=CC2)\C3=CC=C(SC)C=C3

-20°C

Ice Packs

Small Compound