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Sunitinib - CAS 557795-19-4

Sunitinib - CAS 557795-19-4

MF-0003444-01

$32.42 USD
$32.42 USD
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Product Details

  • Bioactivity

    Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase (RTK) inhibitor that inhibits VEGFR2 and PDGFRβ (IC50=80/2 nM) . It exhibits antitumor activity and is used for treating kidney cancer and gastrointestinal tumors.

  • Target

    VEGFR, Apoptosis, FLT, Autophagy, Mitophagy, IRE1, PDGFR, c-Kit

  • Related Pathways

    Tyrosine Kinase/Adaptors, Angiogenesis, Apoptosis, Autophagy, Cell Cycle/Checkpoint

  • CAS Number

    557772

  • Purity

    0.9967

  • Molecular Formula

    C22H27FN4O2

  • Molecular Weight

    398.47

  • SMILES

    C(=C\1/C=2C(NC1=O)=CC=C(F)C2)\C3=C(C)C(C(NCCN(CC)CC)=O)=C(C)N3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound