SW016789 - CAS 292613-04-8

SW016789 is a potent high-secretion inducer targeting VDAC1, which directly stimulates insulin secretion and calcium ion influx in β cells. It transiently induces endoplasmic reticulum stress (ER stress) without causing β cell death. The response it triggers is reversible and non-apoptotic, making SW016789 useful for studying β cell dysfunction in type 2 diabetes (T2DM) .

VDAC

Membrane transporter/Ion channel

292613-04-8

C20H19N3OS

349.45

N=C1N(C=2C=CC=CC2N1CC(O)C=3SC=CC3)CC=4C=CC=CC4

-20°C

Ice Packs

Small Compound