SW116 free base - CAS 1036759-00-8

SW116 free base is a selective fluorescent ligand for the sigma-2 receptor (sigma-2 receptor), with a Ki of 14 nM. It exhibits a maximum excitation wavelength of 333 nM and a maximum emission wavelength of 506 nM in methanol. SW116 free base can internalize into MDA-MB-435 cells, reaching 50% of its maximum fluorescence intensity within 24 minutes. This compound serves as a fluorescent probe in cancer research.

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1036759-00-8

C39H56N4O5S

692.95

S(NCCCCCCCCCCN1[C@]2(C[C@H](OC(NC3=C(OC)C=CC(C)=C3)=O)C[C@@]1(CCC2)[H])[H])(=O)(=O)C=4C5=C(C(N(C)C)=CC=C5)C=CC4

-20°C

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Dye-Reagents