SW203668 (trifluoroacetate salt) - CAS 2117405-48-6

SW203668 is an irreversible inhibitor of stearoyl-CoA desaturase (IC50 = 54 nM) . It is selectively cytotoxic to H2122, H460, HCC44, and HCC95 cell lines that express cytochrome P450 (CYP) isoform CYP4F11 over eight other cancer cell lines that lack CYP4F11 in vitro (IC50s = 22-116 and >10,000 nM, respectively) and ectopic expression of CYP4F11 in SW203668-insensitive H1155 cells results in sensitization to SW203668.

Others, Antibacterial

Others, Microbiology/Virology

2117351

C24H20F3N3O4S

503.49

O=C(O)C(F)(F)F.O=C(NC1=NC=2C=CC(OC)=CC2S1)C3=CC=C(C=C3)C(N)C=4C=CC=CC4

-20°C

Ice Packs

Small Compound