SWS1 - CAS 2922115-32-8

SWS1, a d- (+) -biotin-conjugated PD-L1 inhibitor (IC50: 1.8 nM), displays anticancer activity by augmenting tumor-infiltrating lymphocytes and demonstrating anti-tumor efficacy, as evidenced by a 66.1% tumor growth inhibition (TGI=66.1%) in the B16-F10 mouse model [1].

PD-1/PD-L1, Monoamine Oxidase

Apoptosis, Neuroscience, Immunology/Inflammation, Cell Cycle/Checkpoint

2922075

C47H53ClN6O5S

849.48

C(CCCC(NCCNC(=O)C1N(CC2=C(OCC3=CC(C#N)=CC=C3)C=C(OCC4=C(C)C(=CC=C4)C5=CC=CC=C5)C(Cl)=C2)CCCC1)=O)[C@H]6[C@@]7([C@](CS6)(NC(=O)N7)[H])[H]

-20°C

Ice Packs

Small Compound