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SWTX-143 - CAS 2766575-48-6
SWTX-143 - CAS 2766575-48-6
SKU:MF-0099930-01
Regular price
$276.39 USD
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$276.39 USD
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Product Details
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Bioactivity
SWTX-143, a novel covalent inhibitor, specifically and irreversibly binds to the palmitoylation pocket of all four TEAD isoforms, inhibiting the transcriptional activity of the YAP/TAZ-TEAD complex and demonstrating antitumor activity [1].
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Target
YAP
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Related Pathways
Stem Cells
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CAS Number
2766575-48-6
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Molecular Formula
C19H18F3N3O
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Molecular Weight
361.36
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SMILES
O=C(C=C)NC1CC=2C(N)=CC=CC2N(C3=CC=C(C=C3)C(F)(F)F)C1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound