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Molfinity

SWTX-143 - CAS 2766575-48-6

SWTX-143 - CAS 2766575-48-6

SKU:MF-0099930-01

Regular price $276.39 USD
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  • Bioactivity

    SWTX-143, a novel covalent inhibitor, specifically and irreversibly binds to the palmitoylation pocket of all four TEAD isoforms, inhibiting the transcriptional activity of the YAP/TAZ-TEAD complex and demonstrating antitumor activity [1].

  • Target

    YAP

  • Related Pathways

    Stem Cells

  • CAS Number

    2766575-48-6

  • Molecular Formula

    C19H18F3N3O

  • Molecular Weight

    361.36

  • SMILES

    O=C(C=C)NC1CC=2C(N)=CC=CC2N(C3=CC=C(C=C3)C(F)(F)F)C1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound