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Molfinity

SY-5609 - CAS 2417302-07-7

SY-5609 - CAS 2417302-07-7

MF-0012261-01

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Product Details

  • Bioactivity

    SY-5609 (CDK7-IN-3) is a selective non-covalent CDK7 inhibitor (Kd value is 0.07 nM), with weak inhibitory activity against CDK2, CDK9 and CDK12 with IC50 values ​​of 5.5, 1.9 and 1.7 μM, respectively, and has anti-tumor activity and inhibits cell apoptosis.

  • Target

    Apoptosis, CDK

  • Related Pathways

    Apoptosis, Cell Cycle/Checkpoint

  • CAS Number

    2417302-07-7

  • Purity

    >99.99%

  • Molecular Formula

    C23H26F3N6OP

  • Molecular Weight

    490.46

  • SMILES

    C(F)(F)(F)C=1C(C=2C=3C(NC2)=C(P(C)(C)=O)C(C#N)=CC3)=NC(N[C@H]4CCC(C)(C)NC4)=NC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound