Sydowinin B - CAS 58450-00-3

Sydowinin B is a xanthone polyketide that has been found inA. sydowiiand has immunosuppressant activity.1It inhibits LPS- or concanavalin A-induced proliferation of isolated mouse splenic lymphocytes (IC50s = 19.2 and 20.8 μg/ml, respectively) .2Sydowinin B inhibits superoxide generation in, and elastase release from, isolated human neutrophils induced by cytochalasin B and N-Formyl-Met-Leu-Phe with IC50values of 21.2 and 12.62 μM, respectively.3

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58450-00-3

C16H12O7

316.26

COC(=O)c1c(O)ccc2oc3cc(CO)cc(O)c3c(=O)c12

-20°C

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Small Compound