1
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Molfinity
SYN1143 - CAS 913376-84-8
SYN1143 - CAS 913376-84-8
SKU:MF-0019384-01
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$35.41 USD
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$35.41 USD
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Product Details
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Bioactivity
SYN1143 (AMG-1) is a potent inhibitor of human RON and c-Met.In vitro kinase assays showed that compound I is a potent inhibitor of human RON and c-Met with IC50s of 9 and 4 nmol/L, respectively.
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Target
C-Met/HGFR
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Related Pathways
Tyrosine Kinase/Adaptors
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CAS Number
913284
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Purity
0.9969
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Molecular Formula
C31H29FN4O5
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Molecular Weight
556.58
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SMILES
COc1ccc2c(Oc3ccc(NC(=O)c4c(C)n(CC(C)(C)O)n(-c5ccccc5)c4=O)cc3F)ccnc2c1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound