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Molfinity

SYN1143 - CAS 913376-84-8

SYN1143 - CAS 913376-84-8

SKU:MF-0019384-01

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  • Bioactivity

    SYN1143 (AMG-1) is a potent inhibitor of human RON and c-Met.In vitro kinase assays showed that compound I is a potent inhibitor of human RON and c-Met with IC50s of 9 and 4 nmol/L, respectively.

  • Target

    C-Met/HGFR

  • Related Pathways

    Tyrosine Kinase/Adaptors

  • CAS Number

    913284

  • Purity

    0.9969

  • Molecular Formula

    C31H29FN4O5

  • Molecular Weight

    556.58

  • SMILES

    COc1ccc2c(Oc3ccc(NC(=O)c4c(C)n(CC(C)(C)O)n(-c5ccccc5)c4=O)cc3F)ccnc2c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound