SYUIQ-5 - CAS 188630-47-9

SYUIQ-5 is a ligand for G-quadruplex structures. It plays a role in stabilizing G-quadruplexes and inducing senescence. Additionally, SYUIQ-5 inhibits the activity of the c-myc gene promoter. By displacing TRF2 from telomeres, SYUIQ-5 induces telomeric damage, which triggers autophagy (autophagy) in cancer cells.

DNA/RNA Synthesis, c-Myc, Autophagy

Autophagy, Cell Cycle/Checkpoint, DNA Damage/DNA Repair

188574

C20H22N4

318.415

N=1C=2C=CC=CC2C(NCCCN(C)C)=C3NC=4C=CC=CC4C13

-20°C

Ice Packs

Small Compound