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Molfinity

T-1-PMPA - CAS 1323883-62-0

T-1-PMPA - CAS 1323883-62-0

SKU:MF-0121420-01

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  • Bioactivity

    T-1-PMPA, a potent EGFR inhibitor, demonstrates apoptotic properties and effectively inhibits EGFR WT and EGFR 790m, with IC50 values of 86 nM and 561.73 nM, respectively [1].

  • Target

    EGFR, Apoptosis

  • Related Pathways

    Apoptosis, JAK/STAT signaling, Angiogenesis, Tyrosine Kinase/Adaptors

  • CAS Number

    1323883-62-0

  • Molecular Formula

    C16H17N5O3

  • Molecular Weight

    327.34

  • SMILES

    O=C1C2=C(N(C)C(=O)N1CC(NC3=CC=C(C)C=C3)=O)N=CN2C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound