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T-1-PMPA - CAS 1323883-62-0
T-1-PMPA - CAS 1323883-62-0
SKU:MF-0121420-01
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Product Details
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Bioactivity
T-1-PMPA, a potent EGFR inhibitor, demonstrates apoptotic properties and effectively inhibits EGFR WT and EGFR 790m, with IC50 values of 86 nM and 561.73 nM, respectively [1].
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Target
EGFR, Apoptosis
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Related Pathways
Apoptosis, JAK/STAT signaling, Angiogenesis, Tyrosine Kinase/Adaptors
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CAS Number
1323883-62-0
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Molecular Formula
C16H17N5O3
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Molecular Weight
327.34
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SMILES
O=C1C2=C(N(C)C(=O)N1CC(NC3=CC=C(C)C=C3)=O)N=CN2C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound