T-1095A - CAS 209746-56-5

T-1095A is an active metabolite of T-1095, a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs) . Chronic administration of T-1095 (0.1% w w (-1) pellet chow, for 12 weeks) decreased blood glucose and haemoglobin A (1C) levels, and improved glucose intolerance in db/db mice. Long-term treatment with T-1095 causes sustained improvement in hyperglycemia and prevents diabetic neuropathy in Goto-Kakizaki Rats.

Others, Drug Metabolite

Metabolism, Others

209685

C24H26O9

458.46

C(CCC=1C=C2C(=CC1)OC=C2)(=O)C3=C(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C=C(C)C=C3O

-20°C

Ice Packs

Small Compound