T-Butoxycarbonyl-PEG2-NHS ester - CAS 2411681-93-9

T-Butoxycarbonyl-PEG2-NHS ester features a t-Boc protecting group along with an NHS ester segment. The tert-butyl group can be deprotected under acidic conditions. The NHS ester reacts specifically and efficiently with primary amines, such as lysine residue side chains or amino-silane coated surfaces, under neutral or weakly basic conditions, forming covalent bonds. The hydrophilic PEG linker enhances the compound's solubility in aqueous media.

2411681-93-9

C16H25NO8

359.372

O=C(ON1C(=O)CCC1=O)CCOCCOCCC(=O)OC(C)(C)C

-20°C

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