T-Butyl ester-PEG4-CH2COOH - CAS 929087-83-2

T-Butyl ester-PEG4-CH2COOH is a PEG linker characterized by the presence of a tert-butyl group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of an activator (e.g., HATU) to form a stable amide bond. The hydrophilic PEG spacer improves solubility in aqueous media. The tert-butyl group can be deprotected under acidic conditions.

929087-83-2

C15H28O8

336.378

O=C(O)COCCOCCOCCOCCC(=O)OC(C)(C)C

-20°C

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