T0080 - CAS 2785323-68-2

T0080 is an FPR-1 antagonist. It reduces apoptosis (Apoptosis) and inhibits the production of reactive oxygen species (ROS) and pro-inflammatory cytokines (TNF-α and IL-1β) in plaque macrophages within ApoE−/− mouse models, thereby slowing the progression of atherosclerosis.

Interleukin, Apoptosis, Reactive Oxygen Species

Apoptosis, Immunology/Inflammation, NF-κB, Metabolism

2785253

C24H22F3N3O3

457.45

O=C1C2=NNC(C=3C=C(C=CC3O)C)=C2C(C4=CC=C(C=C4)C(F)(F)F)N1C5CCOCC5

-20°C

Ice Packs

Small Compound