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Molfinity

T2AA - CAS 1380782-27-3

T2AA - CAS 1380782-27-3

MF-0093345-01

$49.62 USD
$49.62 USD
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Product Details

  • Bioactivity

    T2AA (4-[4-[ (2S) -2-amino-3-hydroxypropyl]-2,6-diiodophenoxy]phenol) is an inhibitor of proliferating cell nuclear antigen (PCNA) with IC50 of 1 μM for PCNA/PIP-box peptide interaction. T2AA suppresses cancer cell growth and causes DNA replication stress by stalling DNA replication forks and inhibiting PCNA interaction with DNA polymerase δ.

  • Target

    DNA/RNA Synthesis

  • Related Pathways

    Cell Cycle/Checkpoint, DNA Damage/DNA Repair

  • CAS Number

    1380752

  • Purity

    0.9953

  • Molecular Formula

    C15H15I2NO3

  • Molecular Weight

    511.09

  • SMILES

    N[C@H](CO)Cc1cc(I)c(Oc2ccc(O)cc2)c(I)c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound