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T863 - CAS 701232-20-4
T863 - CAS 701232-20-4
SKU:MF-0094934-01
Regular price
$33.92 USD
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$33.92 USD
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Product Details
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Bioactivity
T-863 (DGAT-1 inhibitor) is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis in cells. IC50 value: Target: DGAT1 T863 (DGAT-3) causes weight loss, reduction in serum and liver triglycerides, and improved insulin sensitivity in obese mice.
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Target
Transferase, Acyltransferase
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Related Pathways
Metabolism
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CAS Number
701208
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Purity
0.9988
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Molecular Formula
C22H26N4O3
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Molecular Weight
394.47
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SMILES
CC1(C)Oc2ncnc(N)c2N=C1c1ccc(cc1)[C@H]1CC[C@H](CC(O)=O)CC1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound