Taccalonolide B - CAS 108885-69-4

Taccalonolide B is effective in vitro against cell lines that overexpress P-glycoprotein (Pgp) and multidrug-resistance protein (MRP7) . Taccalonolide B inhibits growth of SK-OV-3 cells with an IC50 of 208 nM.

Microtubule Associated

Cytoskeletal Signaling

108812

0.9988

C34H44O13

660.71

C[C@@]12[C@@]3([C@]([C@]4([C@](C)([C@@H](OC(C)=O)[C@H]3OC(C)=O)[C@@]5([C@@]([C@@H]4O)([C@]6(C)C(=C[C@H]5C)OC(=O)[C@@]6(C)O)[H])[H])[H])([C@@H](O)C(=O)[C@]1(C[C@]7([C@@]([C@@H]2OC(C)=O)(O7)[H])[H])[H])[H])[H]

-20°C

Ice Packs

Natural Product