Tadalafil-d3 - CAS 960226-55-5

Tadalafil-d3 is a deuterated compound of Tadalafil. Tadalafil has a CAS number of 171596-29-5. Tadalafil is a carboline-based compound with vasodilatory activity. Tadalafil selectively inhibits the cyclic guanosine monophosphate (cGMP) -specific type 5 phosphodiesterase- (PDE-5) -mediated degradation of cGMP, which is found in the smooth muscle of the corpus cavernosa and corpus spongiosum of the penis. Inhibition of cGMP degradation by tadalafil results in prolonged muscle relaxation, vasodilation, and blood engorgement of the corpus cavernosa, and, so, prolonged penile erection.

PDE

Metabolism

960226-55-5

C22H16D3N3O4

392.42

[H][C@]12Cc3c([nH]c4ccccc34)[C@]([H])(N1C(=O)CN(C2=O)C([2H])([2H])[2H])c1ccc2OCOc2c1

-20°C

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