Tagitinin A - CAS 59979-61-2

Tagitinin A is a naturally occurring sesquiterpene lactone compound that acts as a dual agonist of peroxisome proliferator-activated receptor α/γ (PPARα/PPARγ) and exerts antihyperglycemic and antihyperlipidemic effects in diabetes research.Tagitinin A is able to bind directly to the ligand-binding domain of PPARγ (IC50=55 μM), and also stimulates the PPAR Tagitinin A can directly bind to the PPARγ ligand binding domain (IC50=55 μM) and also stimulate the PPARα-dependent activation of the SULT2A1 gene promoter. As a phytotoxin, Tagitinin A significantly inhibited the growth of wheat germ sheath.

Antifection, PPAR

Microbiology/Virology, Metabolism, DNA Damage/DNA Repair

59916

C19H28O7

368.42

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-20°C

Ice Packs

Natural Product