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Molfinity

TAK-285 - CAS 871026-44-7

TAK-285 - CAS 871026-44-7

MF-0012244-01

$33.92 USD
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Product Details

  • Bioactivity

    TAK-285 is a novel dual HER2 and EGFR (HER1) inhibitor with IC50 of 17 nM and 23 nM, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc. Phase 1.

  • Target

    EGFR, HER, Aurora Kinase, MEK

  • Related Pathways

    Cell Cycle/Checkpoint, Angiogenesis, MAPK, Tyrosine Kinase/Adaptors, JAK/STAT signaling, Chromatin/Epigenetic

  • CAS Number

    871026-44-7

  • Purity

    0.9973

  • Molecular Formula

    C26H25ClF3N5O3

  • Molecular Weight

    547.96

  • SMILES

    CC(C)(O)CC(=O)NCCn1ccc2ncnc(Nc3ccc(Oc4cccc(c4)C(F)(F)F)c(Cl)c3)c12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound