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TAK-659 hydrochloride - CAS 1952251-28-3
TAK-659 hydrochloride - CAS 1952251-28-3
SKU:MF-0039390-01
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$34.67 USD
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$34.67 USD
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Product Details
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Bioactivity
TAK-659 hydrochloride (TAK-659) is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM. It is selective against most other kinases, but potent toward both SYK and FLT3.
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Target
VEGFR, FLT, JAK, Tyrosine Kinases, Syk
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Related Pathways
JAK/STAT signaling, Stem Cells, Tyrosine Kinase/Adaptors, Angiogenesis, Chromatin/Epigenetic
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CAS Number
1952220
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Purity
0.9982
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Molecular Formula
C17H22ClFN6O
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Molecular Weight
380.85
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SMILES
Cl.Cn1cc(cn1)-c1nc(N[C@@H]2CCCC[C@@H]2N)c(F)c2CNC(=O)c12
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound