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Taligantinib - CAS 2243235-80-3
Taligantinib - CAS 2243235-80-3
SKU:MF-0118628-01
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Product Details
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Bioactivity
Taligantinib (Compound Example 70) is an orally active and selective dual inhibitor targeting vascular endothelial growth factor receptor 2 (VEGFR-2) and hepatocyte growth factor receptor (c-Met) . It effectively suppresses tumor angiogenesis and cell proliferation, and holds potential for the study of solid tumors such as non-small cell lung cancer and hepatocellular carcinoma.
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Target
VEGFR, c-Met/HGFR
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Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors
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CAS Number
2243152
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Molecular Formula
C35H34F2N4O7
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Molecular Weight
660.66
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SMILES
O=C(NC1=CC=C(F)C=C1)C2(C(=O)NC3=CC=C(OC4=CC=NC5=CC(OCCCN6CCOCC6)=C7OCCOC7=C54)C(F)=C3)CC2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound