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Taligantinib - CAS 2243235-80-3

Taligantinib - CAS 2243235-80-3

SKU:MF-0118628-01

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  • Bioactivity

    Taligantinib (Compound Example 70) is an orally active and selective dual inhibitor targeting vascular endothelial growth factor receptor 2 (VEGFR-2) and hepatocyte growth factor receptor (c-Met) . It effectively suppresses tumor angiogenesis and cell proliferation, and holds potential for the study of solid tumors such as non-small cell lung cancer and hepatocellular carcinoma.

  • Target

    VEGFR, c-Met/HGFR

  • Related Pathways

    Angiogenesis, Tyrosine Kinase/Adaptors

  • CAS Number

    2243152

  • Molecular Formula

    C35H34F2N4O7

  • Molecular Weight

    660.66

  • SMILES

    O=C(NC1=CC=C(F)C=C1)C2(C(=O)NC3=CC=C(OC4=CC=NC5=CC(OCCCN6CCOCC6)=C7OCCOC7=C54)C(F)=C3)CC2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound