Talmapimod hydrochloride - CAS 309915-12-6

Talmapimod hydrochloride is a selective and ATP-competitive p38α inhibitor (IC50: 9 nM) . It also shows about 10-fold selectivity over p38β, and at least 2000-fold selectivity over a panel of 20 other kinases, including other MAPKs.

P38 MAPK

MAPK

309897

C27H31Cl2FN4O3

549.46

Cl.C[C@H]1CN([C@H](C)CN1Cc1ccc(F)cc1)C(=O)c1cc2c(cn(C)c2cc1Cl)C(=O)C(=O)N(C)C

-20°C

Ice Packs

Small Compound