Talotrexin ammonium - CAS 648420-92-2

Talotrexin ammonium is a non-polyglutamic acid antifolate. Talotrexin ammonium inhibits tumor growth by targeting dihydrofolate reductase (DHFR), thereby improving anti-tumor activity in a wide range of cancer models, helping to inhibit tumor growth.

DHFR, Others, Antifolate

Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Others, Metabolism

648326

0.9757

C27H30N10O6

590.59

NC=1C2=C(N=CC(CNC3=CC=C(C(N[C@@H](CCCNC(=O)C4=C(C(O)=O)C=CC=C4)C(O)=O)=O)C=C3)=N2)N=C(N)N1.N

-20°C

Ice Packs

Small Compound