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TAM470 - CAS 1802498-63-0
TAM470 - CAS 1802498-63-0
SKU:MF-0154871-01
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Product Details
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Bioactivity
TAM470, a novel cytolysin, inhibits both tubulin polymerization and microtubule depolymerization. It serves as a precursor in the synthesis of OMTX705, a payload molecule. OMTX705 represents a new class of FAP-targeting antibody-drug conjugates (ADCs) exhibiting antitumor activity [1].
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Target
Microtubule Associated, ADC Cytotoxin
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Related Pathways
Cytoskeletal Signaling, Antibody-drug Conjugate/ADC Related
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CAS Number
1802435
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Molecular Formula
C41H67N7O6S
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Molecular Weight
786.08
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SMILES
CCCO[C@H](C[C@H](C(C)C)N(CCC)C(=O)[C@@H](NC(=O)[C@H]1CCCCN1C)[C@@H](C)CC)c1nc(cs1)C(=O)N[C@H](C[C@H](C)C(=O)NN)Cc1ccc(O)cc1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound