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Tandutinib - CAS 387867-13-2
Tandutinib - CAS 387867-13-2
SKU:MF-0012512-01
Regular price
$38.41 USD
Regular price
$24.70 USD
Sale price
$38.41 USD
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Product Details
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Bioactivity
Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3 versus CSF-1R and >100-fold selectivity for the same target versus FGFR, EGFR, and KDR.
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Target
C-Kit, PDGFR, FLT, Apoptosis, CSF-1R, Src
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Related Pathways
Angiogenesis, Apoptosis, Tyrosine Kinase/Adaptors
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CAS Number
387867-13-2
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Purity
0.9992
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Molecular Formula
C31H42N6O4
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Molecular Weight
562.7
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SMILES
O(C)C1=CC=2C(=NC=NC2C=C1OCCCN3CCCCC3)N4CCN(C(NC5=CC=C(OC(C)C)C=C5)=O)CC4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound