Tandutinib sulfate - CAS 387867-14-3

Tandutinib (MLN518) sulfate is an effective and selective inhibitor of FLT3, with an IC50 value of 0.22 μM. It also inhibits c-Kit and PDGFR, displaying IC50 values of 0.17 μM and 0.20 μM respectively. This compound can be utilized in the treatment of acute myeloid leukemia and has the capability to cross the blood-brain barrier.

Topoisomerase, Drug-Linker Conjugates for ADC, Apoptosis, Microtubule Associated, PDGFR, c-Kit

Apoptosis, Antibody-drug Conjugate/ADC Related, Angiogenesis, DNA Damage/DNA Repair, Tyrosine Kinase/Adaptors, Cytoskeletal Signaling

387850

C31H44N6O8S

660.78

O=C(NC1=CC=C(OC(C)C)C=C1)N2CCN(C=3N=CN=C4C=C(OCCCN5CCCCC5)C(OC)=CC43)CC2.O=S(=O)(O)O

-20°C

Ice Packs

Small Compound