Tanespimycin - CAS 75747-14-7

Tanespimycin (KOS 953) is an Hsp90 inhibitor (IC50=5 nM) and is selective. Tanespimycin depletes intracellular STK38/NDR1 and decreases STK38 kinase activity. Tanespimycin also downregulated stk38 gene expression.

Autophagy, Mitophagy, Apoptosis, HSP, Antibiotic, Antibacterial

Microbiology/Virology, Autophagy, Cytoskeletal Signaling, Apoptosis, Metabolism

75726

0.9983

C31H43N3O8

585.69

CO[C@H]1C[C@H](C)CC2=C(NCC=C)C(=O)C=C(NC(=O)\C(C)=C\C=C/[C@H](OC)[C@@H](OC(N)=O)\C(C)=C\[C@H](C)[C@H]1O)C2=O

-20°C

Ice Packs

Small Compound